Margaret Chen

67F · SH-10284APP

Metabolic-Renal · Retired (librarian)

Next consult

Fri 17 Apr, 09:30

Positive· p 0.84Trending worse

Trajectory headline

Projected to cross cardiorenal decompensation threshold within 3y without SGLT2 initiation.

Model priority

Positive zone

Biggest single change you could makeAdd GLP-1 → −98% (HbA1c)

Patient Context Card · AIME

Brief

Trajectory-grounded orientation for today's appointment.

Cardiorenal trajectory accelerating; eligible for SGLT2 initiation today. Not a routine diabetic review.

Trajectory narrative

Margaret's physiological state has been drifting along the cardiorenal axis for ~11 months. HbA1c trend is modestly worsening, but the dominant driver is declining eGFR coupled with rising UACR. Her wearable-derived BP has been creeping upward against a stable medication list. Horizon-1 projects crossing the cardiorenal decompensation threshold within 3 years on current management.

Active concerns

Declining renal function (eGFR 54 → 48 in 10 months)
Persistent albuminuria (UACR 38 mg/g)
Home BP systolics averaging 145–150 despite dual therapy
HbA1c 8.4% — above target but stable

Suggested consultation focus

Initiate SGLT2 (empagliflozin 10mg) — cardiorenal protection, not glycaemic control
Escalate antihypertensive (add thiazide or increase ACEi)
Repeat UACR — single elevated result, confirm persistence
Discuss trajectory with patient using radar view

Supporting record context

Current medications

Metformin 1g BD · Ramipril 10mg OD · Atorvastatin 40mg ON · Aspirin 75mg OD

Allergies

Penicillin (rash, 1998)

Last admission

Nil in last 24 months

Surgical history

Appendicectomy (2011), Cataract — bilateral (2022/23)

For demonstration purposes. Not a diagnostic tool.

Horizon-1 · Syndrome activation

Latent clinical states

Output of the dynamic hypergraph. Direction = trajectory on that axis.

Cardiorenal

0.81

Metabolic (T2DM)

0.74

Atherosclerotic

0.58

Low-grade inflammatory

0.41

For demonstration purposes. Not a diagnostic tool.

← Practice Horizon

Margaret Chen

67F · SH-10284APP

Metabolic-Renal · Retired (librarian)

Next consult

Fri 17 Apr, 09:30

Positive· p 0.84Trending worse

Trajectory headline

Projected to cross cardiorenal decompensation threshold within 3y without SGLT2 initiation.

Model priority

Positive zone

Biggest single change you could makeAdd GLP-1 → −98% (HbA1c)

Patient Context Card · AIME

Brief

Trajectory-grounded orientation for today's appointment.

Cardiorenal trajectory accelerating; eligible for SGLT2 initiation today. Not a routine diabetic review.

Trajectory narrative

Active concerns

Declining renal function (eGFR 54 → 48 in 10 months)
Persistent albuminuria (UACR 38 mg/g)
Home BP systolics averaging 145–150 despite dual therapy
HbA1c 8.4% — above target but stable

Suggested consultation focus

Initiate SGLT2 (empagliflozin 10mg) — cardiorenal protection, not glycaemic control
Escalate antihypertensive (add thiazide or increase ACEi)
Repeat UACR — single elevated result, confirm persistence
Discuss trajectory with patient using radar view

Supporting record context

Current medications

Metformin 1g BD · Ramipril 10mg OD · Atorvastatin 40mg ON · Aspirin 75mg OD

Allergies

Penicillin (rash, 1998)

Last admission

Nil in last 24 months

Surgical history

Appendicectomy (2011), Cataract — bilateral (2022/23)

For demonstration purposes. Not a diagnostic tool.

Horizon-1 · Syndrome activation

Latent clinical states

Output of the dynamic hypergraph. Direction = trajectory on that axis.

Cardiorenal

0.81

Metabolic (T2DM)

0.74

Atherosclerotic

0.58

Low-grade inflammatory

0.41

For demonstration purposes. Not a diagnostic tool.